Table 3. Medication usage attributable to common chronic disease dyads.
| DYAD | Proportion (%) Daily Oral Medication UseAttributed to Dyad | Total Numberof Daily Oral Medications* | Additional Diagnoses (n) | Overall Prevalence of Dyad (%) |
|---|---|---|---|---|
| ARTH+HTN | 41 | 7.68 ±0.09 | 5.5 | 20 |
| Vasc+HTN | 39 | 7.54 ±0.08 | 5.3 | 26.3 |
| Vasc+CHF | 36 | 8.43 ±0.12 | 5.6 | 10.4 |
| DEP+HTN | 35 | 7.90 ±0.09 | 5.5 | 21 |
| GERD+HTN | 35 | 8.21 ±0.11 | 5.6 | 14.2 |
| Vasc+GERD | 35 | 8.18 ±0.13 | 5.6 | 11.4 |
| Vasc+DEP | 34 | 8.01 ±0.11 | 5.5 | 16.1 |
| Vasc+ARTH | 34 | 7.69 ±0.11 | 5.5 | 15 |
| HTN+THYR | 34 | 8.04 ±0.12 | 5.7 | 9.7 |
| DIA+HTN | 33 | 8.03 ±0.11 | 5.6 | 15.1 |
| ARTH+DEP | 33 | 7.87 ±0.11 | 5.7 | 13.5 |
| HTN+OSTEO | 32 | 8.25 ±0.13 | 5.7 | 9.6 |
| Vasc+DIA | 31 | 8.14 ±0.13 | 5.6 | 12.1 |
| ANEMIA+HTN | 31 | 7.53 ±0.12 | 5.7 | 11.5 |
| HTN+DEM | 30 | 6.73 ±0.08 | 5.3 | 27.4 |
| Vasc+DEM | 28 | 6.66 ±0.09 | 5.3 | 21.1 |
| CHF+HTN | 27 | 8.23 ±0.11 | 5.7 | 12.2 |
| ARTH+DEM | 26 | 6.54 ±0.08 | 5.5 | 17.4 |
| DEP+GERD | 26 | 8.64 ±0.15 | 5.8 | 10.2 |
| COPD+HTN | 25 | 7.76 ±0.14 | 5.7 | 7.9 |
| DEM+THYR | 23 | 6.83 ±0.13 | 5.7 | 9.2 |
| DEM+DEP | 22 | 6.79 ±0.10 | 5.5 | 19.4 |
| DEM+GERD | 21 | 7.23 ±0.13 | 5.6 | 10.7 |
| DEM+OSTEO | 20 | 7.08 ±0.13 | 5.7 | 9.4 |
| ANEMIA+DEM | 15 | 6.61 ±0.13 | 5.7 | 10.3 |
| DEM+DIA | 15 | 7.16 ±0.12 | 5.6 | 10.1 |
Data represent co-morbid 2-disease combinations present in over 5% of either men or women. HTN = hypertension, DEM = dementia, DEP = depression, ARTH = Arthritis, DIA = diabetes mellitus, GERD = gastroesophageal reflux and acid peptic disorders, CHF = congestive heart failure, THYR = thyroid disease, OSTEO = osteoporosis, COPD = chronic obstructive pulmonary disease, Vasc = composite of vascular diseases (atherosclerosis, cerebrovascular disease, coronary artery disease, peripheral artery disease).
*mean ± SEM.