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. Author manuscript; available in PMC: 2019 Apr 1.
Published in final edited form as: Mol Cancer Ther. 2018 Feb 7;17(4):858–868. doi: 10.1158/1535-7163.MCT-17-0965

Figure 2. Carbon ion Spread out Bragg peak, predictions and measurements.

Figure 2

(a) The spinning acrylonitrile butadiene styrene compensator wheel was expected to produce a poly-energetic carbon beam with a 3-cm constant physical dose SOBP (magenta) comprised of 30 individual Bragg peaks (black lines). Dose rate is represented as a function of depth and is normalized to entrance dose rate of mono-energetic 109.5 MeV/12C beam = 1. (b) Monte Carol simulations (blue) and ion chamber dose rate measurements (black-dashed) of the SOBP confirmed a constant physical dose distribution within the target in the proximal SOBP. (c) Monte Carlo simulated dose-weighted LET (orange) is 59-63 keV/μm throughout the proximal SOBP (blue).