Table 3.
Multivariate analyses
| Stage III n = 1247 |
Grade III n = 1189 |
ER-negative 1272 |
Triple-negative n = 979 |
Angiolymphatic Invasion n = 1312 |
|
|---|---|---|---|---|---|
|
| |||||
| OR (95% C.I.) | OR (95% C.I.) | OR (95% C.I.) | OR (95% C.I.) | OR (95% C.I.) | |
|
| |||||
| Menopausal status | |||||
| Pre/peri | Referent | Referent | Referent | Referent | Referent |
| Post | 0.84 (0.44 – 1.60) | 0.80 (0.55 – 1.17) | 0.97 (0.67 – 1.41) | 1.24 (0.70 – 2.22) | 0.80 (0.54 – 1.18) |
| Race | |||||
| White | Referent | Referent | Referent | Referent | Referent |
| Black | 0.91 (0.31 – 2.69) | 2.55 (1.40 – 4.66) | 0.90 (0.49 – 1.65) | 0.46 (0.14 – 1.57) | 1.20 (0.64 – 2.25) |
| Asian/Pacific Islander | 1.43 (0.42 – 4.93) | 0.94 (0.40 – 2.19) | 0.62 (0.25 – 1.52) | 0.82 (0.23 – 2.86) | 1.23 (0.54 – 2.78) |
| Unknown | 2.62 (0.86 – 7.94) | 1.14 (0.46 – 2.82) | 1.31 (0.54 – 3.22) | 2.22 (0.76 – 6.46) | 2.18 (0.97 – 4.88) |
| Ethnicity | |||||
| Hispanic | (Dropped) | 0.96 (0.31 – 2.94) | 1.24 (0.44 – 3.52) | (Dropped) | 0.52 (0.12 – 2.31) |
| Non-Hispanic | Referent | Referent | Referent | Referent | Referent |
| Obesity status | |||||
| Normal weight | Referent | Referent | Referent | Referent | Referent |
| Overweight | 0.99 (0.50 – 1.95) | 1.12 (.77 – 1.61) | 0.89 (0.62 – 1.27) | 0.62 (0.36 – 1.08) | 1.36 (0.93 – 1.99) |
| Obese | 1.36 (0.63 – 2.93) | 1.28 (0.82 – 1.99) | 0.97 (0.63 – 1.50) | 0.51 (0.25 – 1.03) | 0.84 (0.51 – 1.40) |
| Severely obese | 1.85 (0.83 – 4.11) | 1.26 (0.76 – 2.09) | 0.75 (0.44 – 1.26) | 0.39 (0.16 – 0.96) | 1.80 (1.08 – 2.99) |
| Joint test for significance for obesity category test for trend | p = 0.40 | p = 0.69 | p = 0.70 | p = 0.08 | p = 0.03 |
| p = 0.12 | p = 0.25 | p = 0.39 | p = 0.02 | p = 0.14 | |
| Diabetes | 1.46 (0.59 – 3.61) | 0.67 (0.36 – 1.23) | 1.16 (0.63 – 2.12) | 2.03 (0.85 – 4.86) | 1.27 (0.69 – 2.32) |
| Hypertension | 0.85 (0.44 – 1.65) | 1.01 (0.70 – 1.46) | 0.68 (0.47 – 0.98) | 0.82 (0.45 – 1.50) | 0.75 (0.50 – 1.12) |
| HRT | 0.73 (0.37 – 1.43) | 0.82 (0.56 – 1.18) | 1.12 (0.78 – 1.62) | 0.96 (0.54 – 1.69) | 0.98 (0.66 – 1.45) |
| ER status | |||||
| Positive | Referent | Referent | Referent | ||
| Negative | 0.66 (0.33 – 1.31) | 13.15 (9.63 – 17.96) | 0.80 (0.54 – 1.29) | ||
| Unknown | (Dropped) | 2.09 (0.54 – 8.13) | 0.26 (0.03 – 2.06) | ||
| Grade | |||||
| Grade 1 | Referent | Referent | (Dropped) | Referent | |
| Grade 2 | 1.37 (0.63 – 2.97) | 4.89 (2.41 – 9.92) | Referent | 5.12 (2.61 – 10.04) | |
| Grade 3 | 2.39 (1.00 – 5.68) | 47.15 23.28 – 95.50 | 3.64 (2.25 – 5.88) | 8.98 (4.38 – 18.43) | |
| Unknown | 0.32 (0.04 – 2.59) | 8.88 (3.91 – 20.13) | 0.22 (0.03 – 1.61) | 1.02 (0.31 – 3.37) | |
HRT, hormone replacement therapy