Table 1.
Baseline characteristics of newly treated end-stage renal disease patients, by year
| Characteristics | Year groups |
|||||||
|---|---|---|---|---|---|---|---|---|
| Oxfordshire |
All-England |
|||||||
| Oxford Record Linkage Study |
Hospital Episode Statistics (Oxford) |
Hospital Episode Statistics (All-England) |
||||||
| 1970–1990 | 1991–1996 | 2000–2002 | 2003–2005 | 2006–2008 | 2000–2002 | 2003–2005 | 2006–2008 | |
| N | 1220 | 972 | 700 | 750 | 878 | 13,178 | 13,606 | 15,946 |
| Demographics | ||||||||
| Female | 40.2% | 38.0% | 41.1% | 35.9% | 37.7% | 39.5% | 37.9% | 38.5% |
| Median age (yr) | 49 (36–60) | 59 (44–69) | 61 (45–72) | 61 (45–72) | 61 (46–72) | 61 (47–71) | 62 (47–72) | 63 (49–73) |
| 18–40 | 30.2% | 18.7% | 18.7% | 18.7% | 15.9% | 15.8% | 14.8% | 13.0% |
| 40–50 | 21.2% | 15.6% | 13.6% | 13.1% | 14.7% | 13.5% | 13.4% | 12.9% |
| 50–60 | 23.5% | 17.2% | 15.4% | 16.4% | 17.1% | 17.8% | 16.6% | 17.2% |
| 60–70 | 16.8% | 24.2% | 20.7% | 20.8% | 22.1% | 23.1% | 22.9% | 22.7% |
| 70–80 | 7.9% | 20.5% | 24.4% | 23.5% | 19.8% | 23.6% | 24.1% | 24.5% |
| ≥80 | 0.3% | 3.8% | 7.1% | 7.6% | 10.4% | 6.1% | 8.2% | 9.7% |
| Ethnicitya, c | ||||||||
| White | - | - | 86.8% | 86.4% | 84.0% | 82.1% | 81.2% | 79.9% |
| Black | - | - | 3.5% | 3.5% | 4.7% | 6.3% | 6.5% | 6.9% |
| South Asian | - | - | 7.4% | 6.3% | 7.2% | 8.2% | 8.3% | 8.7% |
| Other | - | - | 2.3% | 3.8% | 4.0% | 3.4% | 3.9% | 4.4% |
| Unknown | - | - | 131 | 36 | 35 | 1,694 | 962 | 745 |
| Comorbidities | ||||||||
| Diabetes | 6.7% | 16.8% | 24.4% | 29.2% | 33.9% | 25.7% | 29.9% | 34.3% |
| Vascular | 10.0% | 18.3% | 22.3% | 24.7% | 25.2% | 25.2% | 26.5% | 28.3% |
| Major coronary disease | 2.6% | 4.2% | 5.1% | 7.2% | 8.3% | 6.1% | 7.0% | 7.7% |
| Congestive heart failure | 5.2% | 8.5% | 9.9% | 10.8% | 10.5% | 11.7% | 12.3% | 12.8% |
| Cerebrovascular disease | 1.4% | 2.2% | 3.1% | 2.8% | 3.5% | 3.3% | 3.4% | 3.4% |
| Peripheral arterial disease | 3.0% | 7.8% | 11.3% | 11.5% | 12.9% | 12.0% | 12.5% | 14.2% |
| Nonvascularb | 7.8% | 14.4% | 18.3% | 21.7% | 24.9% | 21.7% | 25.0% | 27.5% |
| Liver disease | 0.5% | 0.4% | 1.7% | 1.1% | 2.3% | 1.6% | 2.0% | 2.8% |
| Cancer | 2.9% | 4.6% | 5.3% | 8.9% | 7.6% | 6.4% | 7.8% | 8.3% |
| Chronic obstructive pulmonary disease | 1.3% | 2.9% | 6.3% | 6.5% | 10.3% | 8.3% | 10.0% | 12.1% |
| Peptic ulcer disease | 1.6% | 2.3% | 2.7% | 1.9% | 1.9% | 2.3% | 2.3% | 2.0% |
| Connective tissue disease | 2.0% | 4.3% | 3.1% | 4.4% | 4.9% | 4.7% | 5.0% | 4.8% |
| Renal characteristicsc | ||||||||
| Initial renal replacement therapy modality | ||||||||
| Dialysis | 94.6% | 92.6% | 93.7% | 92.7% | 91.6% | 94.5% | 94.3% | 93.6% |
| Transplant | 5.4% | 7.4% | 6.3% | 7.3% | 8.4% | 5.5% | 5.7% | 6.4% |
| Primary renal diagnosis (presumed) | ||||||||
| Diabetic kidney disease | 1.6% | 8.4% | 20.0% | 22.5% | 22.1% | 19.1% | 20.1% | 20.4% |
| Glomerulonephritis | 9.3% | 14.1% | 9.3% | 10.8% | 14.5% | 10.8% | 12.2% | 14.1% |
| Polycystic kidney disease | 10.5% | 8.4% | 8.6% | 7.5% | 10.4% | 9.2% | 8.6% | 8.9% |
| Other known diagnosis/unknown | 78.5% | 69.0% | 62.1% | 59.2% | 53.1% | 60.9% | 59.1% | 56.6% |
Excludes patients dying within 90 days. Data are n or % or median (interquartile range).
a
Ethnicity only recorded in Hospital Episode Statistics (92% complete) with percentages quoted only for those with a known ethnicity.
b
Also includes hemiplegia or paraplegia.
c
Not used for standardization. Baseline characteristics of general population hospital controls are in Supplementary Table S3.