Table 2.
Table of clinico-pathological factors used in the nomogram models in the nomogram generating cohort and validation cohort.
| Variable | Original Cohort |
% | Validation Cohort |
% | P value (χ2 test) |
|
|---|---|---|---|---|---|---|
|
| ||||||
| Grade | Low/Intermediate | 104 | 34.6 | 79 | 64.2 | .006 |
| High | 110 | 36.5 | 44 | 35.8 | ||
| NK* | 87 | 28.9 | ||||
|
| ||||||
| LVI | Yes | 67 | 22.2 | 18 | 14.7 | .000 |
| No | 129 | 42.9 | 103 | 83.7 | ||
| NK* | 105 | 34.9 | 2 | 1.6 | ||
|
| ||||||
| PNI | Yes | 99 | 32.9 | 51 | 41.5 | .272 |
| No | 107 | 35.5 | 71 | 57.7 | ||
| NK* | 95 | 31.6 | 1 | 0.8 | ||
|
| ||||||
| Margin | Negative | 113 | 37.5 | 48 | 39.0 | .753 |
| Positive/close | 158 | 52.5 | 72 | 58.5 | ||
| NK* | 30 | 10.0 | 3 | 2.5 | ||
|
| ||||||
| Positive nodes | Yes | 72 | 23.9 | 24 | 19.5 | .268 |
| No | 217 | 72.1 | 97 | 78.9 | ||
| NK* | 12 | 4.0 | 2 | 1.6 | ||
|
| ||||||
| Max tumor size | Mean | 2.5 | 2.2 | .004 | ||
| Range (Min, Max) | (1.5, 3.5) | (1.5, 3.2) | ||||
|
| ||||||
| Clinical T4 | Yes | 32 | 10.6 | 12 | 9.8 | .789 |
| No | 269 | 89.4 | 111 | 90.2 | ||
LVI-Lymphovascular invasion, PNI-Perineural invasion.
*
NK = not known. These patients were not included in statistical test