Table 2.
Outcome | Full unadjusted cohorts
|
Propensity-matched cohorts
|
||||
---|---|---|---|---|---|---|
Historical (N=184) |
Intervention (N=89) |
p-value* | Historical (N=80) |
Intervention (N=80) |
p-value* | |
Intraoperative transfusion rate | 70 (38.0%) | 14 (15.7%) | <0.001 | 28 (35.0%) | 12 (15.0%) | 0.004 |
Postoperative transfusion rate | 16 (8.7%) | 4 (4.5%) | 0.21 | 3 (3.8%) | 3 (3.8%) | 1.00 |
Perioperative transfusion rate | 76 (41.3%) | 16 (18.0%) | <0.001 | 29 (36.2%) | 13 (16.2%) | 0.004 |
Estimated blood loss (mL), Median (IQR) | 500 (250, 800) | 300 (200, 600) | 0.009 | 450 (250, 750) | 300 (200, 500) | 0.021 |
Operative time (min), Mean (SD) | 279.3 (118.6) | 241.7 (105.6) | 0.01 | 264.6 (116.4) | 234.4 (105.9) | 0.09 |
Length of stay (days), Median (IQR) | 4 (3, 6) | 4 (3, 6) | 0.87 | 4 (3, 6) | 4 (3, 6) | 0.66 |
Postoperative complications within 30 days | ||||||
Venous thromboembolism | 3 (1.6%) | 1 (1.1%) | 1.00 | 1 (1.2%) | 1 (1.2%) | 1.00 |
Readmission | 23 (12.5%) | 1 (1.1%) | 0.002 | 6 (7.5%) | 1 (1.2%) | 0.12 |
Reoperation | 8 (4.3%) | 0 | 0.057 | 2 (2.5%) | 0 | 0.50 |
Infection - Pulmonary | 6 (3.3%) | 2 (2.2%) | 1.00 | 3 (3.8%) | 1 (1.2%) | 0.62 |
Infection - Sepsis | 8 (4.3%) | 0 | 0.057 | 1 (1.2%) | 0 | 1.00 |
Infection – Wound or pelvic abscess | 11 (6.0%) | 4 (4.5%) | 0.78 | 2 (2.5%) | 4 (5.0%) | 0.68 |
Unplanned Intensive Care Unit admit | 6 (3.3%) | 0 | 0.18 | 3 (3.8%) | 0 | 0.25 |
Other† | 3 (1.6%) | 0 | 0.55 | 1 (1.2%) | 0 | 1.00 |
Abbreviations: IQR, interquartile range; SD, standard deviation.
Comparisons between groups were evaluated using the chi-square or Fisher’s exact test for nominal variables, the two-sample t-t-est for operative time, and the Wilcoxon rank sum test for estimated blood less and length of stay.
Three patients in the historical cohort had a postop anastomosis leak (n=1), postop perforation and anastomosis leak (n=1), and a small bowel obstruction (n=1), respectively.