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. Author manuscript; available in PMC: 2019 Apr 1.
Published in final edited form as: Chem Biodivers. 2018 Mar 25;15(4):e1800019. doi: 10.1002/cbdv.201800019

Table 2.

Cytotoxicity data of compounds isolated from the roots of S. deserta.

Compound Cytotoxic activitya, IC50 (μM)
A549 MDA-MB-231 KB KB-VIN MCF-7
1 2β, 3β, 24β - trihydroxy - 12, 13 - cyclo - taraxer-l4-en-28oic acid >40 >40 >40 >40 >40
3 6, 7-dehydroroyleanone 6.568±0.176 13.320±1.473 8.916±1.186 8.020±0.258 20.779±1.257
4 horminone 19.354±0.342 23.624±1.812 29.581±1.117 24.455±0.459 34.833±0.922
5 7-O-methylhorminone 7.194±0.260 8.450±0.174 10.281±0.648 7.303±0.285 13.716±0.654
6 sugiol >40 >40 >40 >40 >40
7 demethylcryptojaponol 23.187±0.996 26.243±0.140 23.501±0.960 21.804±0.525 28.590±0.336
8 14-deoxycoleon U 12.249±0.719 18.062±0.008 7.689±0.416 7.707±0.187 8.695±0.975
Paclitaxel (nM)b 4.191±0.493 5.497±0.240 3.529±0.398 2345.602±35.469 11.941±1.305
a

IC50 values based on triplicate five points, presented as the mean ± S.D.

b

Experimental control.