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. Author manuscript; available in PMC: 2018 Apr 24.
Published in final edited form as: ChemMedChem. 2018 Mar 15;13(8):803–815. doi: 10.1002/cmdc.201700824

Figure 3.

Figure 3

Inhibitor 5-bound X-ray structure of HIV-1 protease. The major orientation of the inhibitor is shown. The inhibitor carbon atoms are shown in green, water molecules are red spheres, and the hydrogen bonds are indicated by dotted lines (PDB ID: 6BZ2). Halogen interactions of the fluorine atoms are omitted for clarity.