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. Author manuscript; available in PMC: 2019 May 1.
Published in final edited form as: Liver Transpl. 2018 May;24(5):587–594. doi: 10.1002/lt.25032

Table 4.

Clinical Comparison between Management of Standardized Patients with HE < Grade 2 vs HE Grade ≥2 between specialty trainees vs on-trainees.

<Grade 2 ≥2 Grade
Trainees
%
Non-trainees
%
p value Trainees
%
Non-trainees
%
p value
History
Stool Number 89 73 <0.001 95 86 <0.001
Medication History 90 86 0.31 96 99 0.14
Physical Examination
Neurological examination for focal deficits 26 29 0.27 78 86 0.07
Neurological examination for herniation 0 1 0.43 36 26 0.05
Investigations
MHE Testing 73 66 0.32 15 20 0.23
Brain Scan 3 4 0.67 49 45 0.48
Comprehensive metabolic panel 60 64 0.50 98 99 0.64
Complete blood count 53 58 0.52 99 99 0.83
Blood cultures 2 3 0.70 94 83 <0.001
Urinalysis 10 12 0.73 95 88 0.04
Blood ammonia 7 16 0.03 33 41 0.15
Urine drug screen 22 34 0.05 80 80 0.93
Blood alcohol level 19 29 0.08 72 76 0.41
INR 39 36 0.67 88 91 0.49
Hemoccult 0 12 <0.001 10 31 <0.001
Management (non-specific)
Hospital Admission 2 1 0.64 96 91 0.10
ICU Admission 1 0 1.00 35 29 0.22
Nasogastric intubation 0 0 1.00 25 23 0.75
Endotracheal intubation 0 0 1.00 23 15 0.10
Specific treatments
Lactulose 60 54 0.36 95 91 0.16
Rifaximin 10 20 0.59 68 30 <0.001
Antibiotics 0 0 1.00 17 21 0.32
IV Albumin 0 0 1.00 12 11 0.79
Nutritional management
Nutritional consultation 46 36 0.14 69 64 0.41
Low Protein diet 6 12 0.15 8 18 0.006

P value using Chi-Square or Fisher Exact Test as appropriate MHE: minimal hepatic encephalopathy, ICU: intensive care unit