Table 4.
Clinical Comparison between Management of Standardized Patients with HE < Grade 2 vs HE Grade ≥2 between specialty trainees vs on-trainees.
| <Grade 2 | ≥2 Grade | |||||
|---|---|---|---|---|---|---|
| Trainees % |
Non-trainees % |
p value | Trainees % |
Non-trainees % |
p value | |
| History | ||||||
| Stool Number | 89 | 73 | <0.001 | 95 | 86 | <0.001 |
| Medication History | 90 | 86 | 0.31 | 96 | 99 | 0.14 |
| Physical Examination | ||||||
| Neurological examination for focal deficits | 26 | 29 | 0.27 | 78 | 86 | 0.07 |
| Neurological examination for herniation | 0 | 1 | 0.43 | 36 | 26 | 0.05 |
| Investigations | ||||||
| MHE Testing | 73 | 66 | 0.32 | 15 | 20 | 0.23 |
| Brain Scan | 3 | 4 | 0.67 | 49 | 45 | 0.48 |
| Comprehensive metabolic panel | 60 | 64 | 0.50 | 98 | 99 | 0.64 |
| Complete blood count | 53 | 58 | 0.52 | 99 | 99 | 0.83 |
| Blood cultures | 2 | 3 | 0.70 | 94 | 83 | <0.001 |
| Urinalysis | 10 | 12 | 0.73 | 95 | 88 | 0.04 |
| Blood ammonia | 7 | 16 | 0.03 | 33 | 41 | 0.15 |
| Urine drug screen | 22 | 34 | 0.05 | 80 | 80 | 0.93 |
| Blood alcohol level | 19 | 29 | 0.08 | 72 | 76 | 0.41 |
| INR | 39 | 36 | 0.67 | 88 | 91 | 0.49 |
| Hemoccult | 0 | 12 | <0.001 | 10 | 31 | <0.001 |
| Management (non-specific) | ||||||
| Hospital Admission | 2 | 1 | 0.64 | 96 | 91 | 0.10 |
| ICU Admission | 1 | 0 | 1.00 | 35 | 29 | 0.22 |
| Nasogastric intubation | 0 | 0 | 1.00 | 25 | 23 | 0.75 |
| Endotracheal intubation | 0 | 0 | 1.00 | 23 | 15 | 0.10 |
| Specific treatments | ||||||
| Lactulose | 60 | 54 | 0.36 | 95 | 91 | 0.16 |
| Rifaximin | 10 | 20 | 0.59 | 68 | 30 | <0.001 |
| Antibiotics | 0 | 0 | 1.00 | 17 | 21 | 0.32 |
| IV Albumin | 0 | 0 | 1.00 | 12 | 11 | 0.79 |
| Nutritional management | ||||||
| Nutritional consultation | 46 | 36 | 0.14 | 69 | 64 | 0.41 |
| Low Protein diet | 6 | 12 | 0.15 | 8 | 18 | 0.006 |
P value using Chi-Square or Fisher Exact Test as appropriate MHE: minimal hepatic encephalopathy, ICU: intensive care unit