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Pin1-catalyzed isomerization rates of IRAK-M-pS110 and IRAK-M-S110E peptides
| pIRAK-M-pS110 | IRAK-M-S110E | |
|---|---|---|
| Peptide concentration | 4.4 mM | 4.18 mM |
| PIN1 concentration | 13.8 µM | 20 µM |
| trans/cis ratio (Kisom) | 10.7 | 6.87 |
| kex (s−1) | 28.98 | 0.84 |
| ktc (s−1) | 2.48 | 0.11 |
| kct (s−1) | 26.50 | 0.73 |
