Figure 6.

Neighbor-Joining tree of fungal and animal HECTs. Numbers refer to bootstrap support. Color conventions as in Fig. 5. There are six differences with that Figure, which are indicated with asterisks. For example, HACE1 [*] indicates that at least one sequence included in the HACE1 subfamily in Fig. 5 is missing in the corresponding group in Fig. 6. In this case, the difference consists in just one sequence, Monosiga brevicollis XM_001745698.1, which can be found below in the tree. Four sequences that in this tree appear isolated but were included in one of the subfamilies in Fig. 5 have the name of the corresponding subfamily indicated within brackets. Notice that HUL4A sequences are divided here into three groups instead of two, as in the previous figure.