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. 2018 Apr 23;8:6394. doi: 10.1038/s41598-018-24748-7

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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The schematic presentation of the experimental process of bacterial taxis. (A) The two-chamber device used for the experiments. (B) Normal and cancerous cells were cultivated for 48 hr in separate chambers. (C) GFP-encoding bacteria were injected into the central channel allowing interaction with the diffused biochemical factors from chambers of cell culture. (D) Preferential accumulation of bacteria was quantified in the analysis region by fluorescence intensity of GFP encoding bacteria.