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. 2018 Apr 17;9:391. doi: 10.3389/fphar.2018.00391

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Copyright © 2018 Xiao, Pei, Jiang, Lan, Xiao, Jiang and Wang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Sigmoid E_max relationships between danofloxacin’s antibacterial effect in the blood, liver, spleen, and lung [E, Log₁₀ colony forming units (cfu)/mL or Log₁₀ cfu/g] and the in vivo area under the concentration-time curve from 0 to 24 h (AUC_{24 h})/minimum inhibitory concentration (MIC) ratio in rabbits.