Table 4.
Resources available from the Colon Cancer Family Registry Cohort, as of June 2017
| Males | Females | Total | |||
|---|---|---|---|---|---|
| N (%)f | N (%)f | N (%)f | |||
| Population-based case familiesa | Probands | Baseline questionnaire | 4321 (22.5) | 4419 (18.9) | 8740 (20.6) |
| Food frequency questionnaire | 2096 (22.7) | 2409 (20.5) | 4505 (21.5) | ||
| Blood/buccal samples | 3759 (27.3) | 3886 (22.8) | 7645 (24.8) | ||
| Polyp material | 14 (7.9) | 8 (4.0) | 22 (5.8) | ||
| Cancer material | 3561 (73.6) | 3447 (70.2) | 7008 (71.9) | ||
| Diagnosis and treatment | 1563 (84.2) | 1526 (85.7) | 3089 (85.0) | ||
| Relativesb | Baseline questionnaire | 7740 (40.4) | 10328 (44.3) | 18068 (42.5) | |
| Food frequency questionnaire | 3323 (36.0) | 4700 (40.0) | 8023 (38.3) | ||
| Blood/buccal samples | 4751 (34.4) | 6731 (39.5) | 11482 (37.2) | ||
| Polyp material | 7 (3.9) | 8 (4.0) | 15 (3.9) | ||
| Cancer material | 265 (5.5) | 325 (6.6) | 590 (6.1) | ||
| Diagnosis and treatment | 40 (2.2) | 44 (2.5) | 84 (2.3) | ||
| Spouse controlsc | Baseline questionnaire | 361 (1.9) | 560 (2.4) | 921 (2.2) | |
| Food frequency questionnaire | 135 (1.5) | 197 (1.7) | 332 (1.6) | ||
| Blood/buccal samples | 149 (1.1) | 225 (1.3) | 374 (1.2) | ||
| Population-based control familiesd | Probands | Baseline questionnaire | 2071 (10.8) | 2205 (9.5) | 4276 (10.1) |
| Food frequency questionnaire | 1142 (12.4) | 1023 (8.7) | 2165 (10.3) | ||
| Blood/buccal samples | 1399 (10.1) | 1497 (8.8) | 2896 (9.4) | ||
| Relativesb | Baseline epi data | 310 (1.6) | 467 (2.0) | 777 (1.8) | |
| Food frequency questionnaire | 260 (2.8) | 383 (3.3) | 643 (3.1) | ||
| Blood/buccal samples | 6 (0.0) | 5 (0.0) | 11 (0.0) | ||
| Clinic-based Colon Cancer familiese | Probands with CRCa | Baseline questionnaire | 699 (3.6) | 644 (2.8) | 1343 (3.2) |
| Food frequency questionnaire | 247 (2.7) | 270 (2.3) | 517 (2.5) | ||
| Blood/buccal samples | 645 (4.7) | 625 (3.7) | 1270 (4.1) | ||
| Polyp material | 24 (13.5) | 29 (14.4) | 53 (13.9) | ||
| Cancer material | 561 (11.6) | 526 (10.7) | 1087 (11.2) | ||
| Diagnosis and treatment | 239 (12.9) | 204 (11.5) | 443 (12.2) | ||
| Probands no CRCc | Baseline questionnaire | 137 (0.7) | 304 (1.3) | 441 (1.0) | |
| Food frequency questionnaire | 62 (0.7) | 164 (1.4) | 226 (1.1) | ||
| Blood/buccal samples | 101 (0.7) | 250 (1.5) | 351 (1.1) | ||
| Polyp material | 13 (7.3) | 27 (13.4) | 40 (10.5) | ||
| Cancer material | 20 (0.4) | 67 (1.4) | 87 (0.9) | ||
| Diagnosis and treatment | 0 (0.0) | 0 (0.0) | 0 (0.0) | ||
| Relativesb | Baseline questionnaire | 3524 (18.4) | 4399 (18.9) | 7923 (18.6) | |
| Food frequency questionnaire | 1953 (21.2) | 2596 (22.1) | 4549 (21.7) | ||
| Blood/buccal samples | 2983 (21.6) | 3814 (22.4) | 6797 (22.0) | ||
| Polyp material | 120 (67.4) | 130 (64.4) | 250 (65.8) | ||
| Cancer material | 429 (8.9) | 542 (11.0) | 971 (10.0) | ||
| Diagnosis and treatment | 14 (0.8) | 6 (0.3) | 20 (0.6) | ||
| Total | All population- and clinic-based probands and relatives | Baseline questionnaire | 19163 | 23326 | 42489 |
| Food frequency questionnaire | 9218 | 11742 | 20960 | ||
| Blood/buccal samples | 13793 | 17033 | 30826 | ||
| Polyp material | 178 | 202 | 380 | ||
| Cancer material | 4836 | 4907 | 9743 | ||
| Diagnosis and treatment | 1856 | 1780 | 3636 |
a
Proband had a history of colorectal cancer (CRC) at baseline interview.
b
Affected or unaffected with colorectal cancer at baseline interview.
c
Spouse of proband, had no history of colorectal cancer at baseline interview.
d
Proband had no history of colorectal cancer at baseline interview.
e
Proband was recruited from a family cancer clinic.
f
% of total items obtained. For example 20.6% of all baseline questionnaires completed by probands of population-based case families.