Table 1.
Patient and tumour clinic-pathological characteristics within each TNBC molecular subtype
| Number of samples | ALL (%) | BL1 (%) | IM (%) | LAR (%) | M (%) | MSL (%) | FDR |
|---|---|---|---|---|---|---|---|
| 485 (100) | 122 (25) | 119 (25) | 77 (16) | 102 (21) | 65 (13) | ||
| Age (years old) | |||||||
| <45 | 106 (22) | 40 (33) | 30 (25) | 5 (8) | 18 (18) | 13 (20) | <0.001 |
| ≥45 | 378 (78) | 82 (67) | 89 (75) | 71 (92) | 84 (82) | 52 (80) | <0.001 |
| Tumour size (cm) | |||||||
| ≤2 | 173 (36) | 41 (34) | 44 (37) | 25 (33) | 28 (27) | 35 (54) | 0.018 |
| >2 | 307 (63) | 79 (65) | 74 (62) | 52 (67) | 72 (71) | 30 (46) | 0.033 |
| Unknown | 5 (1) | 2 (2) | 1 (1) | 0 (0) | 2 (2) | 0 (0) | NS |
| Nodal status | |||||||
| Positive | 228 (47) | 63 (52) | 60 (50) | 39 (51) | 35 (34) | 31 (48) | 0.074 |
| Negative | 257 (53) | 59 (48) | 59 (50) | 38 (49) | 67 (66) | 34 (52) | 0.074 |
| Grade | |||||||
| I/II | 65 (13) | 2 (2) | 8 (7) | 19 (25) | 13 (13) | 23 (35) | <0.001 |
| III | 407 (84) | 119 (97) | 109 (92) | 58 (75) | 88 (86) | 33 (51) | <0.001 |
| Unknown | 14 (3) | 1 (1) | 2 (1) | 0 (0) | 1 (1) | 9 (14) | <0.001 |
| Histological type | |||||||
| IDC | 406 (84) | 111 (91) | 97 (81) | 67 (87) | 90 (88) | 41 (63) | <0.001 |
| ILC | 17 (3) | 1 (1) | 2 (2) | 8 (10) | 1 (1) | 5 (8) | 0.001 |
| MED | 28 (6) | 6 (5) | 18 (15) | 2 (3) | 1 (1) | 1 (2) | <0.001 |
| OTHER | 33 (7) | 4 (3) | 2 (2) | 0 (0) | 9 (9) | 18 (28) | <0.001 |
NS, not significant.