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. 2017 Dec 29;59(2):222–233. doi: 10.1093/pcp/pcx210

Fig. 1.

Fig. 1

Benzylisoquinoline alkaloid biosynthetic pathway in California poppy. Solid arrows indicate pathways in which biosynthetic enzyme genes have been identified. Dotted arrows indicate proposed pathways. BBE, berberine bridge enzyme; CYP719A2, stylopine synthase; CYP719A3, stylopine/canadine synthase; CYP719A5, cheilanthifoline synthase; DB10H, dihydrobenzophenanthridine alkaloid 10-hydroxylase; DB12H, dihydrobenzophenanthridine alkaloid 12-hydroxylase; DBOX, dihydrobenzophenanthridine alkaloid oxidase; MSH, N-methylstylopine hydroxylase; OMT, O-methyltransferase; 7OMT, reticuline 7-O-methyltransferase; P450, cytochrome P450; P6H, protopine 6-hydroxylase; SOMT, scoulerine 9-O-methyltransferase; TNMT, tetrahydroprotoberberine N-methyltransferase; SR, sanguinarine reductase.