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B. pseudomallei ΔdsbB is significantly attenuated in a murine model of infection. Groups of 5 mice were challenged via the i.p. route of infection with B. pseudomallei. The impact of dsbB deletion on virulence was assessed for strains K96243 (A and B) and MSHR2511 (C and D). Statistically significant differences were determined by the log rank (Mantel-Cox) test.
