Table 2.
Parameters | Experimental groups | ||||
---|---|---|---|---|---|
Control | EtOH | EtOH + MBSAE-25 | EtOH + MBSAE-50 | EtOH + MBSAE-100 | |
RBC count (106/μl) | 7.88 ± 0.76 | 6.47 ± 0.28 | 7.33 ± 0.41 | 7.47 ± 0.38 | 7.55 ± 0.77 |
Hb (g/dl) | 14.63 ± 0.44 | 9.22 ± 0.21* | 12.56 ± 0.32# | 13.70 ± 0.88# | 14.04 ± 0.90# |
Ht (%) | 47.58 ± 1.71 | 39.66 ± 1.44* | 41.72 ± 1.14 | 43.58 ± 1.77# | 45.36 ± 2.16# |
MCV (mm3/RBC) | 53.61 ± 2.43 | 68. 33 ± 2.71* | 61.44 ± 3. 07 | 58. 33 ± 2.81# | 55. 44 ± 2.09# |
MCH (pg/RBC) | 21.73 ± 1.51 | 19.39 ± 1.66 | 20.19 ± 2.39 | 20.08 ± 2.80 | 21.09 ± 2.26 |
MCHC (g/dl) | 35.09 ± 1.12 | 30.22 ± 1.66* | 32.14 ± 1.85 | 34.12 ± 2. 63# | 34.80 ± 2. 47# |
Plt (103/μl) | 741.70 ± 73.82 | 222.31 ± 72.88* | 620.91 ± 66. 66# | 681.15 ± 68.32# | 711.06 ± 77.12# |
WBC (103/μl) | 10.31 ± 0.45 | 17.21 ± 2.33* | 13.51 ± 0.89# | 12.77 ± 1.08# | 10.81 ± 0.74# |
Animals were daily treated with various doses of the MBSAE (25, 50 and 100 mg kg− 1, b.w., p.o.) or vehicle (NaCl 0.9%) before ethanol (30%, v/v, 10 mL kg− 1, b.w.) intoxication during two months. The data are expressed as mean ± S.E.M. (n = 10), *: p < 0.05 compared to control group and #: p < 0.05 compared to EtOH group
RBC Red blood cell, MCV mean corpuscular volume, MCH mean corpuscular hemoglobin, Hb Hemoglobin, Ht Hematocrit, MCHC mean corpuscular hemoglobin concentration, Plt Platelet and WBC white blood cells