Table 4.
First quartile | Second quartile | Third quartile | Fourth quartile | P for trend | |
---|---|---|---|---|---|
All participants | |||||
Number of participants | 105 | 104 | 105 | 105 | |
Person-years of follow-up | 1019 | 1007 | 983 | 1099 | |
Number of decedents | 22 | 18 | 25 | 11 | |
Death rate per 10,000 person-years | 216 | 179 | 254 | 100 | |
Sex adjusted HR (95%CI) | 1.00 (reference) | 0.84 (0.45–1.56) | 1.23 (0.69–2.19) | 0.42 (0.20–0.87) | 0.080 |
Multivariable adjusted HRa(95%CI) | 1.00 (reference) | 0.81 (0.43–1.54) | 1.26 (0.70–2.26) | 0.46 (0.22–0.96) | 0.149 |
Male | |||||
Number of participants | 57 | 56 | 52 | 63 | |
Person-years of follow-up | 526 | 514 | 476 | 666 | |
Number of decedents | 17 | 16 | 19 | 8 | |
Death rate per 10,000 person-years | 323 | 311 | 399 | 120 | |
Crude HR (95%CI) | 1.00 (reference) | 0.97 (0.49–1.92) | 1.25 (0.65–2.40) | 0.37 (0.16–0.86) | 0.056 |
Multivariable adjusted HRb (95%CI) | 1.00 (reference) | 1.00 (0.49–2.01) | 1.34 (0.68–2.62) | 0.44 (0.19–1.03) | 0.165 |
Female | |||||
Number of participants | 48 | 48 | 53 | 42 | |
Person-years of follow-up | 493 | 493 | 507 | 433 | |
Number of decedents | 5 | 2 | 6 | 3 | |
Death rate per 10,000 person-years | 101 | 41 | 118 | 69 | |
Crude HR (95%CI) | 1.00 (reference) | 0.40 (0.08–2.07) | 1.17 (0.36–3.84) | 0.68 (0.16–2.86) | 0.945 |
Multivariable adjusted HRb (95%CI) | 1.00 (reference) | 0.36 (0.07–1.93) | 1.14 (0.35–3.76) | 0.66 (0.15–3.01) | 0.985 |
HR hazard ratio, CI confidence interval
a Adjusted for sex, body mass index (continuous variable), cigarette smoking (never-smokers, past smokers, current smokers), alcohol intake (non, 1–2 times/week, 3–5 times/week, 6–7 times/week), and medication use (yes, no)
b Adjusted for body mass index (continuous variable), cigarette smoking (never-smokers, past smokers, current smokers), alcohol intake (non, 1–2 times/week, 3–5 times/week, 6–7 times/week), and medication use (yes, no)