Table 1.
Constraints | ||||
Volume | Type | Limit | ||
PTV | Maximum | 105% of Dp | ||
PTV Shell 39 mm | Maximum | 50% of Dp | ||
Patient | Maximum | 105% of Dp | ||
Objectives | ||||
Priority | Volume | Type | Goal | Parameters |
1 | PTV | ↓ LTCP | 0.4 | Dp=45 Gy,α = 4 |
2 | PTV Shell 3 mm | ↓ Maximum | 90% of Dp | |
3 | Left and Right Kidney | ↓ Mean | 8 Gy | |
4 | Liver | ↓ Mean | 15 Gy | |
5 | Heart | ↓ EUD | 15 Gy | k = 6 |
6 | Spinal Cord | ↓ EUD | 25 Gy | k = 12 |
7 | PTV Shell 18 mm | ↓ Maximum | 40% of Dp | |
Skin Ring | ↓ Maximum | 25% of Dp | 21 mm | |
8 | Left and Right Kidney | ↓ Volume-Dose | 25% | 12 Gy |
Liver | ↓ Volume-Dose | 30% | 24 Gy | |
9 | Left and Right Lung | ↓ Volume-Dose | 50% | 20 Gy |
Abbreviations: Dp prescribed dose, LTCP Logarithmic Tumor Control Probability, α cell sensitivity parameter to achieve adequate target coverage, EUD Equivalent Uniform Dose, k volume parameter