FIG 2.

Resistance determinants and mutations identified in patient strains. Known antibiotic resistance determinants (left) are shown together with all other mutations (right) identified between strains. Connecting lines indicate the location of each determinant or mutation in the strain A genome (center). Locations of prophage insertions and 23S rRNA loci are indicated. Mutations matching the daptomycin susceptibility patterns are boxed in red and highlighted in bold. See legend for further details. CIP, ciprofloxacin; LEVO, levofloxacin; DOX, doxycycline; TET, tetracycline; DAP, daptomycin; AMP, ampicillin; PEN, penicillin; CLI, clindamycin; ERY, erythromycin; LZD, linezolid; GEN, gentamicin; VAN, vancomycin.