FIG 3.

Antitoxin is fully protective when administered immediately after symptom onset. (Top) MV values were monitored before and after exposure to 2 RbIMLD₅₀ of BoNT/E with 30 IU/kg of antitoxin (left) or without antitoxin (control) (right). UL, upper limit; LL, lower limit; M, mean. (Bottom) Inhalation profile during the disease course, expressed as MV (liters per minute) by time (seconds). For each time point, the MV value is indicated in a rectangle with a white background (normal) or a gray background (symptomatic). TPE, time postexposure. Data are representative of results from at least 4 treated and 9 untreated control rabbits, collected in 4 independent experiments.