Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Single-dose plasma pharmacokinetics of APX001A. Four different doses of the prodrug APX001 that varied by 4-fold concentrations on a milligram-per-kilogram basis were administered to mice by the oral route. Groups of three mice were sampled for each time point. Each symbol represents the mean ± SD for three animals. Shown in the key is the maximum plasma concentration (Cmax), the area under the concentration curve from time zero to infinity (AUC), and the elimination half-life (t1/2).
