TABLE 4.
Clinical outcome at TOC
| Population | Treatment | No. of patients | No. (%) of patients cured | 95% CI for cure (%) | No. (%) of patients with treatment failure | No. (%) of patients with indeterminate outcomea |
|---|---|---|---|---|---|---|
| MITT | Plazomicin at 10 mg/kg | 12 | 8 (66.7) | 34.9–90.1 | 3 (25.0) | 1 (8.3) |
| Plazomicin at 15 mg/kg | 51 | 36 (70.6) | 56.2–82.5 | 9 (17.6) | 6 (11.8) | |
| Levofloxacin at 750 mg | 29 | 19 (65.5) | 45.7–82.1 | 7 (24.1) | 3 (10.3) | |
| ME | Plazomicin at 10 mg/kg | 7 | 4 (57.1) | 18.4–90.1 | 3 (42.9) | – |
| Plazomicin at 15 mg/kg | 35 | 28 (80.0) | 63.1–91.6 | 7 (20.0) | – | |
| Levofloxacin at 750 mg | 21 | 16 (76.2) | 52.8–91.8 | 5 (23.8) | – |
a
–, patients with missing or indeterminate outcome data were excluded from the ME population.