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Percentage of simulated patients (n = 1,000) with a non-protein-bound plasma concentration exceeding the MIC for ≥50% of the dosing interval (protein binding of 50% was assumed)
Tf50%>MIC = non-protein-bound plasma concentration exceeding the MIC for at least 50% of the dosing interval. Shading indicates that <90% of simulated patients fulfilled the target of Tf50%.
