TABLE 1.

Comparative MICs of omadacycline and comparator agents tested against aerobic dog and cat bite isolates^a

Organism (no. of isolates) and drug	MIC range	MIC50	MIC90
Bergeyella zoohelcum (11)
Omadacycline	≤0.015–0.25	0.06	0.125
Tigecycline	≤0.015–0.125	0.06	0.06
Tetracycline	0.125–0.5	0.25	0.25
Minocycline	0.03–0.06	0.03	0.06
Amoxicillin-clavulanate	≤0.015–0.125	0.03	0.06
Neisseria weaveri (11)
Omadacycline	0.125–0.5	0.25	0.25
Tigecycline	0.03–0.06	0.06	0.06
Tetracycline	0.06–0.25	0.125	0.25
Minocycline	0.03–0.125	0.06	0.125
Amoxicillin-clavulanate	0.03–0.5	0.25	0.25
Neisseria zoodegmatis (11)
Omadacycline	0.125–0.5	0.25	0.5
Tigecycline	0.03–0.125	0.06	0.06
Tetracycline	0.06–0.25	0.125	0.125
Minocycline	0.03–0.125	0.06	0.06
Amoxicillin-clavulanate	0.03–0.5	0.25	0.25
Pasteurella canis (10)
Omadacycline	0.125–0.25	0.25	0.25
Tigecycline	0.03–0.06	0.06	0.06
Tetracycline	0.125–0.25	0.125	0.25
Minocycline	0.06–0.125	0.06	0.125
Amoxicillin-clavulanate	0.06–0.25	0.125	0.125
Pasteurella multocida subsp. multocida (11)
Omadacycline	0.125–0.25	0.25	0.25
Tigecycline	0.03–0.03	0.03	0.03
Tetracycline	0.06–8	0.125	0.25
Minocycline	0.06–0.125	0.06	0.125
Amoxicillin-clavulanate	0.06–0.25	0.25	0.25
Pasteurella multocida subsp. septica (10)
Omadacycline	0.125–0.25	0.25	0.25
Tigecycline	0.03–0.06	0.06	0.06
Tetracycline	0.125–0.25	0.125	0.25
Minocycline	0.03–0.125	0.06	0.06
Amoxicillin-clavulanate	0.125–0.25	0.25	0.25
Staphylococcus pseudintermedius (9)
Omadacycline	0.125–0.125	0.125
Tigecycline	0.06–.06	0.06
Tetracycline	0.125–32	0.125
Minocycline	0.03–4	0.03
Amoxicillin-clavulanate	0.06–2	0.06

^aValues are in micrograms per milliliter.