Table 4.
Treatment characteristics of N-of-1 tests in developing countries
| Variable | Number (%) |
|---|---|
| Type of medical intervention | |
| Traditional medicine | 5 (83%) |
| Modern medicine | 1 (17%) |
| Number of planned treatment cycles | |
| 3 cycles | 6 (100%) |
| Number of crossovers | |
| 2 | 6 (100%) |
| Treatment length | |
| ≥ 2 weeks | 6 (100%) |
| Washout | |
| 5–9 days | 4 (67%) |
| 2 days | 2 (33%) |
| Number of trials blinded | 4 (67%) |
| Outcome measurement (multiple answer) | |
| Patient self-rated symptom score | 6 (100%) |
| Other measurement tools or questionnaires | 5 (83%) |
| Responder definition | |
| P value < 0.05 | 4 (67%) |
| Visual analogue scale (not statistical) difference specified | 2 (33%) |
| Clinical (not statistical) difference specified | 2 (33%) |
| Method of analysis | |
| Pooled analysis (using methods other than Bayesian) | 2 (33%) |
| Wilcoxon signed rank test/non-parametric | 1 (17%) |
| Mean difference | 2 (33%) |
| Paired t test | 4 (67%) |
| Number of individuals who participated | 72 |
| Proportion (%) of individuals completing the trial (completion rate) | 67 (93) |
| Proportion (%) of post-N-of-1 RCTs decisions which favor trial results | 46 (69) |