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. 2018 Apr 23;9:30. doi: 10.1186/s13229-018-0215-7

Table 2.

Unadjusted and adjusted odds ratios (OR [95%CI] per SD of mercury) between prenatal total blood mercury and the extreme levels of autistic traits are shown together with the results of separate analyses for children of mothers who did and those who did not eat fish during pregnancy

Population Autistic trait
Poor social cognition Poor sociability Poor coherence Repetitive behavior
All offspring
 Unadjusted 0.96 [0.87, 1.06] 0.83 [0.74, 0.93] 0.96 [0.86, 1.07] 0.94 [0.87, 1.02]
  N (P) 2331 (0.432) 2898 (0.002) 2249 (0.411) 2528 (0.167)
 Adjusted 0.96 [0.85, 1.08] 0.88 [0.77, 1.01] 1.01 [0.89, 1.14] 0.94 [0.86, 1.04]
  N (P) 1991 (0.459) 2422 (0.073) 1938 (0.912) 2162 (0.234)
Mother ate fish
 Unadjusted 0.95[0.84, 1.06] 0.85 [0.75, 0.97] 1.00 [0.89, 1.13] 0.95 [0.86, 1.04]
  N (P) 1945 (0.355) 2389 (0.015) 1873 (0.985) 2095 (0.228)
 Adjusted 0.92[0.80, 1.05]a 0.89 [0.76, 1.03] 1.04 [0.91, 1.19] 0.93 [0.84, 1.03]
  N (P) 1744 (0.220) 2104 (0.106) 1698 (0.560) 1884 (0.150)
Mother ate no fish
 Unadjusted 1.26 [0.84, 1.87] 0.64 [0.39, 1.05] 0.96 [0.64, 1.45] 1.22[0.90, 1.64]
  N (P) 285 (0.261) 373 (0.079) 273 (0.850) 317 (0.197)
 Adjusted 1.63 [1.02, 2.62] b 0.74 [0.41, 1.35] 0.87 [0.51, 1.48] 1.16 [0.81, 1.66]
  N (P) 240 (0.041) 280 (0.327) 231 (0.598) 272 (0.425)

All associations with P <  0.10 are italicized

aAdjusted for maternal age, parity, family adversity index, housing tenure, household crowding, life events, smoking in pregnancy, prenatal alcohol consumption, and whether child was breastfed

bSignificant interaction between adjusted results for offspring of fish and non-fish eaters