Table 1.
The inhibitory activities of MR crude extract on rat lens aldose reductase (RLAR), DPPH radical scavenging, and advanced glycation end products (AGEs).
| Entry | IC50 (μg/mL)1) | ||
|---|---|---|---|
| RLAR | DPPH | AGEs | |
| 70% MeOH | 4.61 ± 0.29b | 32.39 ± 1.28b | 189.08 ± 4.19b |
| Quercetin2) | 3.65 ± 0.10a | — | — |
| L-Ascorbic acid3) | — | 6.60 ± 0.33a | — |
| Aminoguanidine4) | — | — | 109.10 ± 3.47a |
1)The IC50 values are defined as mean ± relative standard derivation (RSD) of half-maximal inhibitory concentrations obtained from three independent experiments performed in duplicate, and the range of the inhibitor concentrations adopted to evaluate IC50 was prepared as follows: (1) RLAR: 1, 5, and 10 μg/mL; (2) DPPH: 15, 30, and 75 μg/mL; and (3) AGEs: 20, 100, and 200 μg/mL. 2)–4)Quercetin, L-ascorbic acid, and aminoguanidine are the positive control for RLAR inhibition, DPPH scavenging, and AGEs inhibition. Values within a column marked with different letters are significantly different from each other (p < 0.05).