Table 2.
N | Events | HR | Lower CI | Upper CI | P value | |
---|---|---|---|---|---|---|
Total patients | 26,182 | 468 | 0.642 | 0.535 | 0.771 | <0.001 |
Patients with underlying CVD | 6914 | 150 | 0.727 | 0.527 | 1.003 | 0.052 |
Patients without underlying CVD | 19,150 | 330 | 0.591 | 0.476 | 0.735 | <0.001 |
Male | 15,072 | 287 | 0.624 | 0.495 | 0.788 | <0.001 |
Female | 11,100 | 194 | 0.600 | 1.058 | 0.980 | 0.116 |
Patients aged ≥ 65 years | 8718 | 207 | 0.717 | 0.545 | 0.943 | 0.017 |
Patients aged < 65 years | 17,288 | 267 | 0.617 | 0.485 | 0.756 | <0.001 |
Patients with DM microvascular complication | 4326 | 91 | 0.542 | 0.357 | 0.822 | 0.004 |
Patients without DM microvascular complication | 21,740 | 387 | 0.622 | 0.509 | 0.760 | <0.001 |
CI: 95% confidence interval; CVD: cardiovascular disease; DM: diabetes mellitus; DPP-4i: dipeptidyl-peptidase IV inhibitor; HR: hazard ratio; N: number of patients; SU: sulfonylurea.