Table II.
Names of tested interface designs and their respective mutations in the bsAbs B10v5 × hu225M and B10v5 × huOKT3
Design | B10v5 | hu225M or huOKT3 | ||
---|---|---|---|---|
CH1 | CL | CH1 | CL | |
MaB40 | – | – | K26D | T18R |
MaB5/40 | A20L | F7S | K26D | T18R |
MaB21/40 | A20L | F7A | K26D | T18R |
MaB45/40 | A20L | F7V | K26D | T18R |