Table 3.
HMOS (ref. nos. in superscript) | Lactation (days) | No. of mothers/no. of samples | Mean concentration (g/L) | 95%CL (g/L) |
---|---|---|---|---|
Term studies | ||||
2′-FL31–35,42,43,45,71,72 | 0 to > 100 | 353/556 | 2.74 | 2.43–3.04 |
3-FLa31,32,34,42,43,45,48 | 0 to > 100 | 122/365 | 0.44 | 0.31–0.58 |
DF-L31,35,42,43,45,74 | 0 to > 100 | 288/455 | 0.42 | 0.32–0.51 |
LNT31,34,40,42,45,48,72,74 | 0 to 100 | 114/308 | 0.79 | 0.59–0.98 |
LNnT31,34,35,42,48 | 0 to 100 | 184/372 | 0.74 | 0.36–1.12 |
LNFP Ia31,32,34,35,40,42,43,45,48,72 | 0 to > 100 | 331/580 | 1.31 | 1.08–1.53 |
LNFP II31,32,34,35,45,48,74 | 0 to 100 | 229/389 | 0.28 | 0.21–0.34 |
LNFP III31,35,48 | 0 to 100 | 154/246 | 0.33 | 0.24–0.42 |
LNFP V35,48 | 0 to 30 | 133/137 | 0.06 | −0.15 to 0.26 |
LNFP VI48 | 0 to 30 | 4/8 | 0.01 | 0.00–0.02 |
LNDFH Ia31,34,43,48,74 | 0 to > 100 | 61/214 | 0.80 | 0.66–0.94 |
LNDFH II31,32,34,42,43,48 | 0 to > 100 | 76/319 | 0.14 | 0.10–0.18 |
LNH31,34,72 | 0 to 100 | 49/209 | 0.09 | 0.06–0.13 |
LNnH34 | 0 to 100 | 18/90 | 0.16 | 0.06–0.25 |
F-LNH I31 | 0 to 100 | 21/109 | 0.20 | 0.08–0.33 |
F-LNH II31,32,34 | 0 to 100 | 53/176 | 0.27 | 0.14–0.40 |
DF-LNH I31 | 0 to 100 | 21/109 | 0.31 | 0.19–0.43 |
DF-LNH II32,34 | 0 to 100 | 28/100 | 2.31 | 1.93–2.68 |
DF-LNnH34 | 0 to 100 | 18/90 | 0.54 | 0.10–0.98 |
TF-LNH32,34 | 0 to 100 | 28/100 | 2.84 | 2.60–3.07 |
Sum of means | 14.78 | |||
Preterm studies | ||||
2′-FL33,41,46 | 0–60 | 74/230 | 2.77 | 0.76–4.78 |
3-FL33,41,46 | 0–60 | 75/230 | 0.32 | 0.17–0.48 |
DF-L33,41 | 0–60 | 54/190 | 0.41 | 0.17–0.65 |
LNT33,41,46 | 0–60 | 75/356 | 1.04 | 0.39–1.68 |
LNnT33,41,46 | 0–30 | 75/227 | 0.66 | 0.04–1.28 |
LNFP I33,41,46 | 0–60 | 74/230 | 1.09 | 0.39–1.78 |
LNFP II33,41,46 | 0–60 | 68/198 | 0.27 | 0.14–0.40 |
LNFP III33,41,46 | 0–60 | 75/230 | 0.16 | 0.04–0.28 |
LNFP V41 | 0–60 | 12/22 | 0.02 | 0.00–0.04 |
LNDFH II33,41 | 0–60 | 47/168 | 0.07 | 0.00–0.14 |
LNH33 | 0–30 | 42/168 | 0.06 | 0.04–0.08 |
LNnH33 | 0–30 | 42/168 | 0.08 | 0.06–0.11 |
F-LNH II33 | 0–30 | 41/168 | 0.33 | 0.26–0.41 |
DF-LNH II33 | 0–30 | 35/140 | 2.70 | 2.54–2.86 |
DF-para-LNH33 | 0–30 | 35/140 | 0.44 | 0.10–0.79 |
DF-para-LNnH33 | 0–30 | 42/168 | 0.50 | −0.09 to 1.09 |
TF-LNH33 | 0–30 | 35/140 | 0.65 | 0.21–1.08 |
Sum of means | 11.57 |
Abbreviations: CL, confidence limit; ref. nos., reference numbers.
aHMOS exhibiting significant differences between the means of the lactation periods (see Tables S2-A, S2-B, and S2-C in the Supporting Information online).