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. 2018 May;94:104–114. doi: 10.1016/j.ejca.2018.02.014

Table 2.

Summary of published literature relating to the frequency of Epstein-Barr virus in oesophageal cancer.

Reference Year Oesophageal cancer type Total n EBV positive n (%) Method
TCGA [24] 2017 SqC 90 0 Whole-exome sequencing
AdC 70 0
undiff 2 0
Genitsch et al.[34] 2015 AdC 118 0 EBER ISH
Farris et al.[38] 2011 AdC 76 1 (1) EBER ISH
Sunpaweravong et al.[36] 2005 SqC 104 0 EBER ISH
Wu et al.[39] 2005 SqC 151 6 (4) EBER ISH
undiff 13 4 (31)
Awerkiew et al.[40] 2003 SqC 23 8 (35) PCR
AdC 14 5 (36)
Yanai et al.[33] 2003 SqC 34 0 EBER ISH, PCR
Mizobuchi et al.[37] 1997 SqC 41 0 PCR
Wang et al.[35] 1999 SqC 51 0 EBER ISH, PCR
Wang et al.[41] 1999 SqC 31 11 (36) EBER ISH, PCR

Abbreviations: AdC, adenocarcinoma; SqC, squamous cell carcinoma; EBER ISH, EBV-encoded RNA in situ hybridisation; PCR, polymerase chain reaction; undiff, undifferentiated.