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. 2018 Jan 2;17(3):309–318. doi: 10.1080/15384101.2017.1407894

Figure 1.

Figure 1.

The qRT-PCR analysis of miR-424-5p expression in EOC tissues and cell lines. (A) The expression of miR-424-5p was significantly downregulated in 83 EOC tissues, compared to normal ovarian tissues (**p<0.01). (B) The downregulation of miR-424-5p significantly differ between HGSC and LGSC in different histological subtypes of EOC. (**p<0.01). (C) The expression levels of miR-424-5p in ovarian cancer cell lines were all significantly lower than in the normal cell line. Data were shown by mean±SEM from three independent experiments, where appropriate, **p<0.01. (D) Overall or (E)relapse-free Kaplan-Meier survival analysis for miR-424-5p expression revealed that down-regulated miR-424-5p is associated with poor prognosis in 83 EOC patients (p = 0.012, p = 0.020).