Skip to main content
. 2018 Jan 2;17(3):309–318. doi: 10.1080/15384101.2017.1407894

Figure 2.

Figure 2.

Effect of miR-424-5p on cellular proliferation and cycle distribution. (A) Levels of miR-424-5p in A2780 and HO8910 cells were analyzed 24 h after mimics or inhibitor transfection. (B) Overexpression of miR-424-5p suppresses EOC cell growth. Cell viability was measured by CCK-8 assay on 24, 48, 72, 96 hours after miR-424-5p mimics, inhibitor and its controls transfected in A2780 and HO8910 cells, respectively. (C) Upregulation of miR-424-5p promotes G1/S transition in A2780, and downregulation of miR-424-5p arrests G1/S transition in HO8910, compared with the corresponding controls. (D) No significant difference between A2780 and HO8910 each treated with miR-424-5p mimics, inhibitor and its control groups in apoptosis. The data were shown by mean±SEM from three independent experiments, where appropriate, *p<0.05; **p<0.01.