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. 2018 Apr 20;8(4):e020871. doi: 10.1136/bmjopen-2017-020871

Table 2.

Main barriers and enablers to start, intensify, continue or deprescribe antihypertensive medication

Enabler Barrier
Starting AHM
 High SBP (> 180  mm Hg) Age > 80  years
 History of CVD/DM Limited life expectancy

 Planned operation
Frailty
 Patient preference Psychological impact of starting medication
Patient preference
Intensifying AHM
 High SBP (>140 or >160  mm Hg) Age> 80  years
 Age <80 years ≥3 antihypertensive drugs
 History of CVD/DM Patient preference
Frailty
Continuing AHM
 Automated prescription routines
 Time constraints
 Requires less justification than deprescribing/intensifying
 Anticipating discomfort when disturbing the precarious balance
 Target BP level not yet reached
Deprescribing AHM
 Prolonged achievement of target BP Anticipated regret
 Side effects, orthostatic hypotension Deprescribing may give the impression of giving up on a patient
 Risk of falling AHM gives patients a sense of control
 Patient preference
 Experience with increase in quality of life
 Terminal illness

AHM, antihypertensive medication; BP, blood pressure; CVD, cardiovascular disease; DM, diabetes mellitus; SBP, systolic blood pressure.