Table 2.
Main barriers and enablers to start, intensify, continue or deprescribe antihypertensive medication
| Enabler | Barrier |
| Starting AHM | |
| High SBP (> 180 mm Hg) | Age > 80 years |
| History of CVD/DM | Limited life expectancy |
| Planned operation |
Frailty |
| Patient preference | Psychological impact of starting medication |
| Patient preference | |
| Intensifying AHM | |
| High SBP (>140 or >160 mm Hg) | Age> 80 years |
| Age <80 years | ≥3 antihypertensive drugs |
| History of CVD/DM | Patient preference |
| Frailty | |
| Continuing AHM | |
| Automated prescription routines | |
| Time constraints | |
| Requires less justification than deprescribing/intensifying | |
| Anticipating discomfort when disturbing the precarious balance | |
| Target BP level not yet reached | |
| Deprescribing AHM | |
| Prolonged achievement of target BP | Anticipated regret |
| Side effects, orthostatic hypotension | Deprescribing may give the impression of giving up on a patient |
| Risk of falling | AHM gives patients a sense of control |
| Patient preference | |
| Experience with increase in quality of life | |
| Terminal illness | |
AHM, antihypertensive medication; BP, blood pressure; CVD, cardiovascular disease; DM, diabetes mellitus; SBP, systolic blood pressure.