Table 3.

TILs PD1 protein and mRNA expression and their relationship with clinicopathological features.

		Protein			mRNA
	Clinical Parameters	positive	negative	P value	Positive	Negative	P value
age							0.333
	<50	67	24	0.417	17	23
	≥50	61	30		10	24
Tumor size				0.247			0.557
	≤2cm	54	20		5	17
	>2cm≤5cm	70	29		30	39
	>5cm	3	4		0	4
P53				0.519			1.000
	positive	66	25		13	23
	negative	61	29		14	24
Ki-67 index				0.012			0.487
	<20%	17	16		2	14
	≥20%	111	38		12	37
tumor cells PDL1				0.112			0.013
	Positive	12	1		25	33
	Negative	116	53		1	14
TILs amount				0.001			0.164
	<30%	89	49		11	47
	≥30%	38	4		3	4
TILs PDL1 positivity				0.000			0.003
	Positive	57	3		20	18
	negative	71	51		6	29
Basallike subtype				0.025			0.298
	Yes	108	37		21	30
	No	20	17		6	17
Histological type				0.084			0.716
	Invasive carcinoma of non-specific subtype	120	46		23	42
	others	8	8		4	5
grade				0.113			0.618
	Grade1 or 2	34	21		8	17
	Grade 3	94	33		19	30
Stage				0.550			0.492
	I	36	11		1	10
	II	66	31		10	29
	III	26	12		3	12
Lymphnode metastasis				0.245			1.000
	Yes	49	27		12	23
	No	73	26		13	22
Distant metastasis				0.000			0.084
	Yes	25	27		7	23
	No	97	26		20	24