Table 3.

Summary of autophagy-relevant GO gene set enrichment analysis (GSEA) results from a dataset of drug-naïve, sporadic Parkinson disease patients.

GO Identifier	GO Term Name
GO:0005776	autophagosome
GO:0000421	autophagosome membrane
GO:0000407	phagophore assembly site
GO:0034045	phagophore assembly site membrane
GO:0006914	autophagy
GO:1905037	autophagosome organization
GO:0044804	autophagy of nucleus
GO:0016236	macroautophagy
GO:1903008	organelle disassembly
GO:0061726	mitochondrion disassembly

Analysis was performed as detailed in Materials and Methods. Gene sets relevant to autophagy and enriched in patients vs. controls at nominal P value <5% were selected from Tables S3, S4 and S5, and sorted by false discovery rate (smallest first). Note that the label of GO:0044804 (currently ‘autophagy of nucleus’) was previously ‘nucleophagy’, and has been modified recently to be more consistent with literature usage.