Table 2. Basic information of candidate SNPs in this study.
SNP | Gene | Chr | Allels(A/B) | p-HWE | MAF | OR | 95% CI | P | |
---|---|---|---|---|---|---|---|---|---|
Case | Control | ||||||||
rs11674595 | IL1R2 | 2q11.2 | C/T | 0.408 | 0.289 | 0.243 | 1.16 | 0.88–1.53 | 0.217 |
rs4851527 | IL1R2 | 2q11.2 | A/G | 0.697 | 0.382 | 0.296 | 0.89 | 0.70–1.15 | 0.320 |
rs719250 | IL1R2 | 2q11.2 | T/C | 0.103 | 0.365 | 0.269 | 0.89 | 0.69–1.15 | 0.293 |
rs3218896 | IL1R2 | 2q11.2 | C/T | 0.478 | 0.997 | 0.136 | 1.00 | 0.71–1.40 | 0.136 |
rs3218977 | IL1R2 | 2q11.2 | G/A | 0.357 | 0.532 | 0.226 | 0.92 | 0.70–1.20 | 0.242 |
rs2072472 | IL1R2 | 2q11.2 | G/A | 0.129 | 0.224 | 0.243 | 1.19 | 0.90–1.56 | 0.213 |
rs10490571 | IL1R1 | 2q12.1 | T/C | 0.549 | 0.026 | 0.219 | 1.40 | 1.04–1.87 | 0.167 |
rs956730 | IL1R1 | 2q12.1 | A/G | 0.352 | 0.729 | 0.230 | 0.95 | 0.73–1.25 | 0.239 |
rs3917225 | IL1R1 | 2q12.1 | T/C | 0.716 | 0.217 | 0.400 | 1.16 | 0.92–1.47 | 0.365 |
rs3917318 | IL1R1 | 2q12.1 | G/A | 0.910 | 0.054 | 0.442 | 0.80 | 0.63–1.00 | 0.498 |
rs3783550 | IL1A | 2q13 | T/G | 0.532 | 0.612 | 0.357 | 1.06 | 0.84–1.36 | 0.342 |
rs3783546 | IL1A | 2q13 | C/G | 0.532 | 0.612 | 0.357 | 1.06 | 0.84–1.36 | 0.342 |
rs2856838 | IL1A | 2q13 | A/G | 0.875 | 0.106 | 0.275 | 1.24 | 0.95–1.62 | 0.234 |
rs1609682 | IL1A | 2q13 | T/G | 0.532 | 0.593 | 0.357 | 1.07 | 0.84–1.36 | 0.342 |
rs3783521 | IL1A | 2q13 | G/A | 0.532 | 0.612 | 0.357 | 1.06 | 0.84–1.36 | 0.342 |
rs2853550 | IL1B | 2q13 | A/G | 0.318 | 0.996 | 0.092 | 1.00 | 0.67–1.49 | 0.092 |
rs1143643 | IL1B | 2q13 | C/T | 0.910 | 0.427 | 0.462 | 0.91 | 0.72–1.15 | 0.486 |
rs3136558 | IL1B | 2q13 | G/A | 0.480 | 0.593 | 0.381 | 0.94 | 0.74–1.19 | 0.396 |
rs1143630 | IL1B | 2q13 | T/G | 0.176 | 0.581 | 0.166 | 0.92 | 0.67–1.25 | 0.178 |
rs1143627 | IL1B | 2q13 | G/A | 0.142 | 0.488 | 0.519 | 1.09 | 0.86–1.37 | 0.498 |
rs16944 | IL1B | 2q13 | A/G | 0.114 | 0.405 | 0.475 | 0.91 | 0.72–1.14 | 0.500 |
rs1143623 | IL1B | 2q13 | G/C | 0.132 | 0.746 | 0.409 | 0.96 | 0.76–1.22 | 0.419 |
Abbreviations: SNP: single nucleotide polymorphism, Alleles A/B: Minor/major alleles; MAF, minor allele frequency; OR: odds ratio, CI: confidence interval, HWE: Hardy–Weinberg equilibrium.
p ≤ 0.05 indicates statistical significance.