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. 2017 Dec 11;9(26):17994–18001. doi: 10.18632/oncotarget.23157

Table 2. Basic information of candidate SNPs in this study.

SNP Gene Chr Allels(A/B) p-HWE MAF OR 95% CI P
Case Control
rs11674595 IL1R2 2q11.2 C/T 0.408 0.289 0.243 1.16 0.88–1.53 0.217
rs4851527 IL1R2 2q11.2 A/G 0.697 0.382 0.296 0.89 0.70–1.15 0.320
rs719250 IL1R2 2q11.2 T/C 0.103 0.365 0.269 0.89 0.69–1.15 0.293
rs3218896 IL1R2 2q11.2 C/T 0.478 0.997 0.136 1.00 0.71–1.40 0.136
rs3218977 IL1R2 2q11.2 G/A 0.357 0.532 0.226 0.92 0.70–1.20 0.242
rs2072472 IL1R2 2q11.2 G/A 0.129 0.224 0.243 1.19 0.90–1.56 0.213
rs10490571 IL1R1 2q12.1 T/C 0.549 0.026 0.219 1.40 1.04–1.87 0.167
rs956730 IL1R1 2q12.1 A/G 0.352 0.729 0.230 0.95 0.73–1.25 0.239
rs3917225 IL1R1 2q12.1 T/C 0.716 0.217 0.400 1.16 0.92–1.47 0.365
rs3917318 IL1R1 2q12.1 G/A 0.910 0.054 0.442 0.80 0.63–1.00 0.498
rs3783550 IL1A 2q13 T/G 0.532 0.612 0.357 1.06 0.84–1.36 0.342
rs3783546 IL1A 2q13 C/G 0.532 0.612 0.357 1.06 0.84–1.36 0.342
rs2856838 IL1A 2q13 A/G 0.875 0.106 0.275 1.24 0.95–1.62 0.234
rs1609682 IL1A 2q13 T/G 0.532 0.593 0.357 1.07 0.84–1.36 0.342
rs3783521 IL1A 2q13 G/A 0.532 0.612 0.357 1.06 0.84–1.36 0.342
rs2853550 IL1B 2q13 A/G 0.318 0.996 0.092 1.00 0.67–1.49 0.092
rs1143643 IL1B 2q13 C/T 0.910 0.427 0.462 0.91 0.72–1.15 0.486
rs3136558 IL1B 2q13 G/A 0.480 0.593 0.381 0.94 0.74–1.19 0.396
rs1143630 IL1B 2q13 T/G 0.176 0.581 0.166 0.92 0.67–1.25 0.178
rs1143627 IL1B 2q13 G/A 0.142 0.488 0.519 1.09 0.86–1.37 0.498
rs16944 IL1B 2q13 A/G 0.114 0.405 0.475 0.91 0.72–1.14 0.500
rs1143623 IL1B 2q13 G/C 0.132 0.746 0.409 0.96 0.76–1.22 0.419

Abbreviations: SNP: single nucleotide polymorphism, Alleles A/B: Minor/major alleles; MAF, minor allele frequency; OR: odds ratio, CI: confidence interval, HWE: Hardy–Weinberg equilibrium.

p ≤ 0.05 indicates statistical significance.