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. 2018 Apr 6;9(26):18041–18052. doi: 10.18632/oncotarget.24710

Figure 2. Qualitative analysis of cytocidal effect of OAd-hamIFN combined with chemotherapies.

Figure 2

Combinations of OAd-hamIFN with 5-FU, CDDP, and GEM were analyzed for the cytocidal effect by the Crystal Violet assay in HP1 and PGHAM hamster pancreatic cancer cell lines. In both cell lines, combination of virus and chemotherapy showed superior cell killing compared to cytotoxicity of virus or chemotherapy alone. The killing effect was improved with increasing of virus and chemotherapy doses. VP: viral particle.