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. 2018 Apr 6;9(26):18069–18083. doi: 10.18632/oncotarget.24725

Figure 3. Effect of the ABC exposure to gene expressions of TJ/AJ and EMT.

Figure 3

The expression of ZO-1 in AGS with the 24-hour stimulation of weak acid, bile acid, and ABC was investigated. (A) RT-qPCR demonstrated that, compared to control, the expression of ZO-1 mRNA was significantly inhibited in the group stimulated by weak acid or bile acid, and even more significantly inhibited in the ABC-stimulated group (P < 0.05, N = 5, Turkey-Kramer HSD test). (B) The expressions of TJ/AJ proteins were investigated in Western blot analyses.