Table 3. Statistically significant associations based on single studies (P-value threshold E-06).
| Reference | Cancer type | Genes | SNP ID | Ref/Alt | Chr | OR [95%CI] | P-value | location | eQTL | eQTL P-value skeletal muscle |
|---|---|---|---|---|---|---|---|---|---|---|
| Postel-Vinay S. [10] | Ewing's | C1orf127, TARDBP | rs9430161 | T/G | 1 | 2.20 [1.80, 2.70] | 1.40E-20 | intergene | ||
| Postel-Vinay S. [10] | Ewing's | C1orf127 | rs2003046 | A/C | 1 | 1.80 [1.50, 2.20] | 1.30E-14 | intron | ||
| Postel-Vinay S. [10] | Ewing's | C1orf127 | rs11576658 | T/C | 1 | 1.80 [1.40, 2.30] | 9.40E-11 | intron | ||
| Postel-Vinay S. [10] | Ewing's | SRP14-AS1 | rs4924410 | C/A | 15 | 1.50 [1.30, 1.70] | 6.60E-09 | intron | RP11-521C20.2 | 1.60E-07 |
| Grünewald TG. [29] | Ewing's | ADO, EGR2 | rs10995305 | G/A | 10 | 1.59 [1.26, 2.00] | 4.38E-07 | intergene | ADO | 1.40E-16 |
| Zhao J. [97] | Osteo | ARHGAP35 | rs1052667 | C/T | 19 | 2.25 [1.64, 3.09] | 4.43E-07 | utr 3 prime | ARHGAP35 | Other tissue |
| Grünewald TG. [29] | Ewing's | ADO, EGR2 | rs224290 | G/C | 10 | 0.55 [0.43, 0.70] | 7.80E-07 | intergene | ADO | 7.50E-14 |
| Grünewald TG. [29] | Ewing's | ADO, EGR2 | rs224291 | G/A | 10 | 0.55 [0.43, 0.70] | 7.80E-07 | intergene | ADO | 7.20E-14 |
| Grünewald TG. [29] | Ewing's | ADO, EGR2 | rs224296 | C/T | 10 | 0.55 [0.43, 0.70] | 7.80E-07 | intergene | ADO | 2.90E-14 |
| Grünewald TG. [29] | Ewing's | ADO, EGR2 | rs224297 | T/C | 10 | 0.55 [0.43, 0.70] | 7.80E-07 | intergene | ADO | 2.80E-14 |
| Grünewald TG. [29] | Ewing's | ADO, EGR2 | rs224298 | G/A | 10 | 0.55 [0.43, 0.70] | 7.80E-07 | intergene | ADO | 2.90E-14 |
| Grünewald TG. [29] | Ewing's | ADO, EGR2 | rs224294 | C/T | 10 | 0.54 [0.43, 0.69] | 1.01E-06 | intergene | ADO | 5.60E-14 |
| Grünewald TG. [29] | Ewing's | ADO, EGR2 | rs224293 | G/A | 10 | 0.55 [0.44, 0.71] | 1.02E-06 | intergene | ADO | 7.20E-14 |
| Grünewald TG. [29] | Ewing's | EGR2, ADO | rs1848796 | C/T | 10 | 1.80 [1.42, 2.29] | 1.08E-06 | intergene | ADO | 2.90E-14 |
| Grünewald TG. [29] | Ewing's | ADO, EGR2 | rs224282 | A/G | 10 | 0.55 [0.44, 0.71] | 1.08E-06 | intergene | ADO | 7.20E-14 |
| Savage SA. [11] | Osteo | ADAMTS17 | rs2086452 | T/C | 15 | 1.35 [1.19, 1.52] | 1.12E-06 | intron | ||
| Grünewald TG. [29] | Ewing's | EGR2 | rs648746 | G/T | 10 | 0.56 [0.44, 0.71] | 1.21E-06 | upstream | ADO | 5.10E-15 |
| Grünewald TG. [29] | Ewing's | EGR2 | rs648748 | G/A | 10 | 0.56 [0.44, 0.71] | 1.21E-06 | upstream | ADO | 5.10E-15 |
| Grünewald TG. [29] | Ewing's | EGR2 | rs7076924 | A/G | 10 | 1.79 [1.41, 2.28] | 1.21E-06 | upstream | ADO | 5.50E-15 |
| Grünewald TG. [29] | Ewing's | EGR2 | rs224277 | T/C | 10 | 0.56 [0.44, 0.71] | 1.40E-06 | upstream | ADO | 3.30E-15 |
| Grünewald TG. [29] | Ewing's | ADO, EGR2 | rs224289 | T/C | 10 | 0.56 [0.44, 0.71] | 1.42E-06 | intergene | ADO | 7.20E-14 |
| Grünewald TG. [29] | Ewing's | ADO, EGR2 | rs7096645 | G/T | 10 | 1.78 [1.40, 2.27] | 1.54E-06 | intergene | ADO | 8.60E-14 |
| Grünewald TG. [29] | Ewing's | LOC107984012, NRBF2 | rs10740101 | A/G | 10 | 2.07 [1.55, 2.76] | 2.29E-06 | intergene | ADO | 4.90E-10 |
| Grünewald TG. [29] | Ewing's | EGR2, LOC107984012 | rs7079482 | C/T | 10 | 2.06 [1.54, 2.76] | 2.69E-06 | intergene | ADO | 1.70E-10 |
| Grünewald TG. [29] | Ewing's | EGR2, LOC107984012 | rs1115705 | T/C | 10 | 2.07 [1.55, 2.77] | 2.73E-06 | intergene | ADO | 9.40E-11 |
| Grünewald TG. [29] | Ewing's | EGR2, LOC107984012 | rs983319 | A/T | 10 | 2.07 [1.55, 2.77] | 2.99E-06 | intergene | ADO | 4.10E-10 |
| Grünewald TG. [29] | Ewing's | EGR2, LOC107984012 | rs1571918 | A/G | 10 | 2.05 [1.54, 2.74] | 3.44E-06 | intergene | ADO | 2.80E-10 |
| Grünewald TG. [29] | Ewing's | EGR2, LOC107984012 | rs1888968 | C/T | 10 | 2.05 [1.54, 2.74] | 3.44E-06 | intergene | ADO | 1.90E-10 |
| Grünewald TG. [29] | Ewing's | EGR2, LOC107984012 | rs1912369 | G/A | 10 | 2.05 [1.54, 2.74] | 3.44E-06 | intergene | ADO | 3.50E-10 |
| Grünewald TG. [29] | Ewing's | EGR2, LOC107984012 | rs4147153 | A/G | 10 | 2.05 [1.54, 2.74] | 3.44E-06 | intergene | ADO | 3.50E-10 |
| Grünewald TG. [29] | Ewing's | EGR2, LOC107984012 | rs4237316 | C/T | 10 | 2.05 [1.54, 2.74] | 3.44E-06 | intergene | ADO | 1.90E-10 |
| Grünewald TG. [29] | Ewing's | EGR2, LOC107984012 | rs4746746 | C/T | 10 | 2.05 [1.54, 2.74] | 3.44E-06 | intergene | ADO | 7.20E-10 |
| Grünewald TG. [29] | Ewing's | EGR2, LOC107984012 | rs6479854 | C/T | 10 | 2.05 [1.54, 2.74] | 3.44E-06 | intergene | ADO | 1.50E-10 |
| Grünewald TG. [29] | Ewing's | EGR2, LOC107984012 | rs7100213 | T/C | 10 | 2.05 [1.54, 2.74] | 3.44E-06 | intergene | ADO | 2.10E-10 |
| Grünewald TG. [29] | Ewing's | EGR2, LOC107984012 | rs4746745 | T/C | 10 | 2.03 [1.52, 2.72] | 3.48E-06 | intergene | ADO | 5.90E-11 |
| Grünewald TG. [29] | Ewing's | ADO, EGR2 | rs224301 | G/A | 10 | 0.60 [0.47, 0.76] | 3.67E-06 | intergene | ADO | 1.20E-10 |
| Grünewald TG. [29] | Ewing's | ADO, EGR2 | rs224302 | G/A | 10 | 0.60 [0.47, 0.76] | 3.67E-06 | intergene | ADO | 3.70E-10 |
| Grünewald TG. [29] | Ewing's | ADO, EGR2 | rs10822056 | C/T | 10 | 1.65 [1.31, 2.09] | 3.70E-06 | intergene | ADO | 3.00E-13 |
| Grünewald TG. [29] | Ewing's | ADO, EGR2 | rs224295 | A/C | 10 | 0.60 [0.48, 0.76] | 4.80E-06 | intergene | ADO | 1.50E-10 |
| Grünewald TG. [29] | Ewing's | ADO, EGR2 | rs224299 | T/C | 10 | 0.60 [0.48, 0.76] | 4.80E-06 | intergene | ADO | 1.50E-10 |
| Savage SA. [11] | Osteo | LOC105373401, LOC105373402 | rs13403411 | C/T | 2 | 1.30 [1.16, 1.46] | 5.20E-06 | intergene | ||
| Grünewald TG. [29] | Ewing's | EGR2, LOC107984012 | rs1509952 | C/T | 10 | 2.06 [1.54, 2.76] | 5.28E-06 | intergene | ADO | 3.50E-10 |
| Grünewald TG. [29] | Ewing's | LOC107984012 | rs10740095 | T/C | 10 | 2.03 [1.52, 2.72] | 5.50E-06 | intron | ADO | 4.20E-11 |
| Grünewald TG. [29] | Ewing's | LOC107984012 | rs925307 | T/C | 10 | 2.03 [1.52, 2.72] | 5.50E-06 | intron | ADO | 6.00E-11 |
| Grünewald TG. [29] | Ewing's | EGR2, LOC107984012 | rs7073383 | A/G | 10 | 2.01 [1.50, 2.69] | 5.98E-06 | intergene | ADO | 1.60E-10 |
| Grünewald TG. [29] | Ewing's | EGR2, LOC107984012 | rs10733780 | G/T | 10 | 2.01 [1.50, 2.69] | 6.90E-06 | intergene | ADO | 2.90E-10 |
| Grünewald TG. [29] | Ewing's | LOC107984012 | rs7071512 | T/C | 10 | 2.01 [1.50, 2.69] | 6.90E-06 | intron | ADO | 4.20E-11 |
| Savage SA. [11] | Osteo | FAM208B, GDI2 | rs2797501 | A/G | 10 | 0.62 [0.51, 0.77] | 7.88E-06 | missense, downstream | ||
| Savage SA. [11] | Osteo | DLEU1, LOC107984568 | rs573666 | G/A | 13 | 0.77 [0.68, 0.86] | 8.59E-06 | intergene | EBPL | Other tissue |
| Grünewald TG. [29] | Ewing's | EGR2, LOC107984012 | rs10740097 | C/T | 10 | 2.03 [1.51, 2.72] | 9.03E-06 | intergene | ADO | 1.20E-10 |
| Grünewald TG. [29] | Ewing's | LOC107984012 | rs6479848 | T/C | 10 | 2.01 [1.50, 2.69] | 9.16E-06 | intron | ADO | 2.70E-11 |
| Grünewald TG. [29] | Ewing's | ZNF365, ADO, EGR2 | rs224079 | C/T | 10 | 1.58 [1.25, 2.01] | 9.24E-06 | intergene | ADO | 5.00E-22 |
| Grünewald TG. [29] | Ewing's | LOC107984012 | rs965128 | C/T | 10 | 1.99 [1.49, 2.66] | 9.48E-06 | intron | ADO | 3.10E-11 |
OR [95%CI]: Odds Ratio [95% Confidence Interval]; Ref: reference allele; Alt: alternative allele; eQTL: expression quantitative trait locus.