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. 2017 Nov 6;9(25):17309–17324. doi: 10.18632/oncotarget.22457

Table 2. KEGG pathway analysis of differentially expressed up and down regulated gene (fold change > 1.75) in three contrast groups, (E11_VS_E16, E11_VS_P1, E16_VS_P1).

Contrast
group
Pathway Count P-value q-value
E11_VS_E16 Glycolysis/Gluconeogenesis 3 3.28E-05 5.97E-06
Calcium signaling pathway 4 4.79E-05 7.98E-06
Glyoxylate and dicarboxylate metabolism 2 1.10E-04 1.63E-05
Reductive carboxylate cycle (CO2
fixation)
2 1.10E-04 1.63E-05
Oxidative phosphorylation 3 5.09E-04 5.66E-05
Citrate cycle (TCA cycle) 2 6.43E-04 6.76E-05
Pyruvate metabolism 2 9.75E-04 9.75E-05
Cysteine metabolism 1 0.011454 9.54E-04
E11_VS_P1 Citrate cycle (TCA cycle) 6 3.65E-12 2.44E-12
Pyruvate metabolism 5 2.10E-09 8.41E-10
Glycolysis / Gluconeogenesis 5 9.91E-09 3.30E-09
Oxidative phosphorylation 5 1.06E-06 2.12E-07
Butanoate metabolism 3 1.12E-05 1.67E-06
Wnt signaling pathway 4 5.15E-05 5.72E-06
Valine, leucine and isoleucine biosynthesis 2 5.77E-05 6.07E-06
Cysteine metabolism 2 7.68E-05 7.31E-06
Propanoate metabolism 2 7.44E-04 5.51E-05
Calcium signaling pathway 3 0.001658 1.08E-04
MAPK signaling pathway 3 0.004502 2.43E-04
Apoptosis 2 2 0.005367 2.75E-04
E16_VS_P1 Citrate cycle (TCA cycle) 5 7.51E-12 6.14E-12
Glycolysis / Gluconeogenesis 4 2.40E-08 1.20E-08
Pyruvate metabolism 3 1.57E-06 4.49E-07
Cysteine metabolism 2 1.38E-05 2.75E-06
Oxidative phosphorylation 3 6.24E-05 1.04E-05
Arginine and proline metabolism 2 1.71E-04 2.44E-05
Glycine, serine and threonine
metabolism
2 2.89E-04 3.85E-05
Alkaloid biosynthesis I ___ 1 0.004309 4.42E-04
Nucleotide sugars metabolism 1 0.004309 4.42E-04
Valine, leucine and isoleucine
biosynthesis
1 0.005025 4.79E-04
Phenylalanine, tyrosine and tryptophan
biosynthesis
1 0.006457 5.61E-04
Glyoxylate and dicarboxylate
metabolism
1 0.007886 6.31E-04
Reductive carboxylate cycle (CO2
fixation)
1 0.007886 6.31E-04
Pentose and glucuronate inter conversions 1 0.0086 6.37E-04