Table 2. Frequencies of KIR genes and HLA allele and haplotypes among individuals with symptomatic acute encephalitis and healthy subjects.
| KIR haplotypes | Subjects with acute encephalitis (n: 30) | Subjects without acute encephalitis (n: 36) | p | |
|---|---|---|---|---|
|
AA AB + BB |
19 (63.3) 11 (36.7) |
8 (22.2) 28 (77.8) |
0.001 | |
| KIR alleles | ||||
| 2DL1 (n/%) | 30 (100) | 31 (86.1) | 0.034 | |
| 2DL2 (n/%) | 12 (40) | 18 (50) | 0.41 | |
| 2DL3 (n/%) | 30 (100) | 36 (100) | ||
| 2DL4 (n/%) | 30 (100) | 36 (100) | ||
| 2DL5A (n/%) | 6 (20) | 6 (16.6) | 0.72 | |
| 2DL5B (n/%) | 3 (10) | 6 (16.6) | 0.43 | |
| 2DS1 (n/%) | 9 (30) | 10 (27.7) | 0.84 | |
| 2DS2 (n/%) | 5 (16.6) | 12 (33.3) | 0.12 | |
| 2DS3 (n/%) | 3 (10) | 8 (22.2) | 0.18 | |
| 2DS4 (n/%) | 19 (63.3%) | 32 (88.8) | 0.011 | |
| 2DS5 (n/%) | 6 (20) | 19 (52.7) | 0.006 | |
| 3DL1 (n/%) | 30 (100) | 32 (88.8) | 0.060 | |
| 3DL2 (n/%) | 30 (100) | 36 (100) | - | |
| 3DL3 (n/%) | 30 (100) | 36 (100) | - | |
| 3DS1 (n/%) | 6 (20) | 22 (61.1) | 0.001 | |
| 2DP1 (n/%) | 30 (100) | 36 (100) | - | |
| 3DP1 (n/%) | 30 (100) | 36 (100) | - | |
| HLA-A-Bw4 (n/%) | 12 (40) | 3 (8.3) | 0.003 | |
| HLA-B-Bw4T (n/%) | 13 (43.3) | 8 (22.2) | 0.067 | |
| HLA-B-Bw4I (n/%) | 5 (16.6) | 7 (19.4) | 1.0 | |
| HLA- C1 (n/%) | 21 (70) | 22 (61.1) | 0.45 | |
| HLA- C2 (n/%) | 23 (76.6) | 13 (36.1) | 0.001 | |
KIR: Killer-cell immunoglobulin-like receptors; HLA: human leukocyte antigen.