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. 2018 Apr 3;9(25):17554–17563. doi: 10.18632/oncotarget.24785

Table 2. Correlation between plasma PD-L1 levels and patients’ characteristics.

Patients characteristic PD-L1 classes (based on medianvalue) - N (%) p value
negative positive
Age 0.58
 ≤70.4 13 (46.4) 15 (53.6)
 >70.4 11 (39.3) 17 (60.7)
Gender 0.86
 Male 16 (42.1) 22 (57.9)
 Female 8 (44.4) 10 (55.6)
Smoking history 0.71
 Never/Former 19 (44.2) 24 (55.8)
 Current 5 (38.5) 8 (61.5)
Number of metastaticsites 0.06
 1 2 (50.0) 2 (50.0)
 2 8 (50.0) 8 (50.0)
 3 11 (47.8) 12 (52.2)
 4 2 (25.0) 6 (75.0)
 5 1 (33.3) 2 (66.7)
 6 0 (0.0) 2 (100.0)
EGFR status 0.97
 Mutateda 5 (45.5) 6 (54.5)
 Wild type 17 (45.9) 20 (54.1)
KRAS status 0.42
 Mutatedb 5 (38.5) 8 (61.5)
 Wild type 13 (52.0) 12 (48.0)
ALK status 0.79
 Rearranged 1 (50.0) 1 (50.0)
 Wild type 15 (40.5) 22 (59.5)
ROS1 status 0.36
 Rearranged 1 (100.0) 0 (0.0)
 Wild type 6 (33.3) 12 (66.7)

aEGFR mutations included: exon 18 = 1 (9.0%); exon 19 = 4 (36.4%); exon 20 = 2 (18.2%); exon 21 = 4 (36.4%); bKRAS mutations included: codon 12 = 13 (100%).