Table 3. Differences in pathologic, mutational and mRNA levels in gene expression groups.
Groups | Location | Cell type | DOG1 staining |
Mutational state |
KIT Expression |
---|---|---|---|---|---|
I (n = 13) | Gastric: 11 | Epithelioid: 10 | Positive: 9 | PDGFRA: 6 | : 23.46 |
Others: 2 | Others: 3 | Negative: 0 | KIT: 2 | High: 13/13 | |
N/A: 4 | Wild Type: 5 | Low: 0/13 | |||
II (n = 19) | Gastric: 4 | Epithelioid: 4 | Positive: 1 | PDGFRA: 1 | : 1.76 |
Others: 15 | Others: 15 | Negative: 17 | KIT: 5 | High: 3/19 | |
N/A: 1 | Wild Type: 13 | Low: 16/19 | |||
p < 0.001 | |||||
Groups | PDGFRA | DOG1 | IGF1R | MIR221 | MIR222 |
Expression | Expression | Expression | Expression | Expression | |
I (n = 13) | : 2.96 | : 111.97 | : 0.44 | : 0.02 | : 3.16 |
High: 11/13 | High: 13/13 | High: 4/13 | High: 4/11 | High: 2/10 | |
Low: 2/13 | Low: 0/13 | Low: 9/13 | Low: 7/11 | Low: 8/10 | |
II (n = 19) | : 0.26 | : 2.02 | : 0.98 | : 0.09 | : 9.14 |
High: 5/19 | High: 3/19 | High: 12/19 | High: 11/18 | High: 11/17 | |
Low: 14/19 | Low: 16/19 | Low: 7/19 | Low: 7/18 | Low: 6/17 | |
p = 0.005 | p < 0.001 | p = 0.018 | p = 0.15 | p = 0.11 |
N/A: Not Available. : Median.