Table 6. Univariate and multivariate analysis of factors predicting disease-free survival in postmenopausal women.

Factor	Univariate			Multivariate
	RRa	95% CIb	P	RRa	95% CIb	P
BMI	1.02	0.91–1.15	0.68
Tumor size	2.3	1.00–5.27	0.05
Lymph node status	1.65	1.01–2.69	0.04*	1.46	1.10–1.93	0.008*
Tumor grade	3.3	1.31–8.34	0.01*	1.13	0.33–3.95	0.84
Ki67 LI	1.07	1.03–1.11	<0.001*	1.05	1.02–1.12	0.005*
ER	1.01	0.99–1.04	0.40
PgR	0.98	0.96–1.00	0.05
AR	1.00	0.98–1.01	0.71
VDR	1.00	0.95–1.02	0.53
pAKT (<170, 170≥)	3.17	1.18–8.54	0.02*	0.27	0.07–1.01	0.05
pER (<15%, 15%≥)	0.27	0.09–0.79	0.02*	2.49	0.73–8.51	0.14
PIK3CA mutation	0.21	0.06–0.73	0.02*	0.14	0.03–0.76	0.02*
Adjuvant chemotherapy	0.77	0.10–5.84	0.80
Adjuvant endocrine therapy	1.5	0.48–4.66	0.48

LI: labeling index; pAKT: AKT phospho-Ser473; pER: ERα phospho-Ser167.

^aRelative risk.

^bConfidence interval.

^*P < 0.05 is considered significant.