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. 2018 Apr 3;9(25):17770–17796. doi: 10.18632/oncotarget.24880

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Copyright: © 2018 Özenver et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License 3.0 (CC BY 3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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(A) Cytotoxicity of doxorubicin towards acute lymphoblastic cells by means for the resazurin assay. Doxorubicin was used as control drug. (B) Cytotoxicity of Aloe-emodin towards CCRF-CEM cells by means of protease viability marker assay. This assay was used as independent method for the resazurin assay. (C) Toxicity of Aloe-emodin in normal PBMC cells by means of the resazurin assay. These cells served as negative control to prove, whether or not Aloe-emodin inhibits tumor cells in a non-specific manner.