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. 2017 Sep 29;125(9):097026. doi: 10.1289/EHP1699

Table 4.

Adjusted mortality hazard ratios (95% confidence intervals) for alternative Cox models using nearest-road traffic volume exposures, 100-m buffer.

Exposure: Traffic volumes of nearest road (vh/24h) Alternative Cox model
Cox model with only individual-level covariatesa Add group-level household incomeb to adjusted model Add group-level smoking estimatesc to adjusted model Exclude non-microbiologically confirmed casesa Exclude patients who moved within Californiaa Left-censored values: Assign zero instead of missinga
n 18,396 18,375 14,478 14,404 17,480 32,832
Q1 (HR) 1.00 1.00 1.00 1.00 1.00 1.00
Q2 [HR (95% CI)] 1.03 (0.86, 1.25) 1.03 (0.86, 1.24) 1.13 (0.91, 1.40) 1.05 (0.87, 1.28) 1.05 (0.87, 1.27) 1.00
Q3 [HR (95% CI)] 1.14 (0.95, 1.37) 1.14 (0.95, 1.36) 1.23 (1.00, 1.52) 1.16 (0.96, 1.40) 1.16 (0.96, 1.40) 0.90 (0.79, 1.02)
Q4 [HR (95% CI)] 1.19 (0.99, 1.43) 1.19 (0.99, 1.43) 1.29 (1.05, 1.59) 1.20 (1.00, 1.46) 1.21 (1.01, 1.46) 1.01 (0.90, 1.14)
Q5 [HR (95% CI)] 1.28 (1.07, 1.53) 1.27 (1.06, 1.52) 1.41 (1.16, 1.75) 1.28 (1.06, 1.54) 1.28 (1.07, 1.54) 1.10 (0.98, 1.23)
p-Trend 0.002 0.003 <0.001 0.004 0.002 0.04

Note: CI, confidence interval; HR, hazard ratio; p-Trend, the p-value for the trend across quintiles of traffic exposure; Q1–Q5, quintiles 1 through 5, where Q5 is the highest quintile of traffic exposure; vh, vehicle.

a

Adjusted for individual-level covariates: age, sex, race, ethnicity, foreign birth, recent immigration within 5 y prior to tuberculosis (TB) diagnosis, population density, region of residence, unemployment within one year before TB diagnosis, homeless within one year before TB diagnosis, excess recreational drug and/or alcohol use within one year before TB diagnosis, and HIV infection.

b

Group-level covariate: census block group median annual household income.

c

Group-level covariate: census tract smoking prevalence estimates.