Risk factors for progression of MCI to normal cognition, vascular or mixed dementia, or Alzheimer-type dementia. APOE, apolipoprotein; CDR-sob, Clinical Dementia Rating scale sum of boxes; CLU, clusterin; HIS, Hachinski Ischemic Score; MMSE, Mini-Mental Status Examination; MCI, mild cognitive impairment; MTL, medial temporal lobe; t-Tau, total Tau protein from cerebrospinal fluid; WML, white matter lesions.